Repurposing antidepressants and phenothiazine antipsychotics as efflux pump inhibitors in cancer and infectious diseases

HIGHLIGHTS

  • who: Bu00e1lint Ru00e1cz and Gabriella Spengler from the Department of Medical Microbiology, Albert Szent-Gyu00f6rgyi Health Center, Albert Szent-Gyu00f6rgyi Medical School, University of Szeged, Semmelweis utca, Szeged, Hungary have published the article: Repurposing Antidepressants and Phenothiazine Antipsychotics as Efflux Pump Inhibitors in Cancer and Infectious Diseases, in the Journal: Antibiotics 2023, 12, 137 Modulation of mTOR-signaling of /2023/
  • what: In modulating review,of the authors aim totricyclic present antidepressants an overview of the antibacterial, anticancer, and efflux pump activity SSRIs, (TCAs), and phenothiazine-type antipsychotics modulating activity . ics.

SUMMARY

     

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