Rescue of mitochondrial sirt3 ameliorates ischemia-like injury in human endothelial cells

HIGHLIGHTS

  • who: Xi Liu and collaborators from the State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China Tongji University, Shanghai, China have published the research work: Rescue of Mitochondrial SIRT3 Ameliorates Ischemia-like Injury in Human Endothelial Cells, in the Journal: (JOURNAL)
  • what: The authors compared the role of these two proteins in ischemia-associated endothelial injury and unexpectedly found that mitochondrial SIRT3, but not nuclear SIRT1, could prevent OGD/R-induced endothelial injury.
  • how: The results . . .

     

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