HIGHLIGHTS
- who: FTD and collaborators from the Charles Perkins Centre, The University of Sydney, Camperdown have published the research work: RESEARCH Open Access, in the Journal: (JOURNAL)
- what: The authors demonstrate that both FTD-GRN and FTDC9orf72 are characterised by significant lipid loss in frontal white matter.
- future: It will be important in future studies to determine whether the lipidomic signature and pronounced myelin loss in FTD-GRN cases is shared with a subset of sporadic FTD cases with TDP-43 inclusions. Research is required to determine if impaired fatty_acid oxidation is a feature . . .
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