HIGHLIGHTS
SUMMARY
More than 4 billion doses of mRNA_vaccines have been administered globally, accounting for approximately onethird of the total number of immunizations. mRNA_vaccines not only induce high levels of humoral immunity, but also elicit relatively strong cellular immune_responses. Owing to the rapidness and editability of the mRNA_vaccine technology, it is suitable for use as a vaccine platform to tackle emerging infectious diseases. frontiersin.org 10.3389/fimmu.2022.1091797 surge in research interest in linear RNA. All of the aforementioned COVID-19 mRNA_vaccines possess a linear structure. The successful development and application of COVID-19 . . .
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