Resiquimod-mediated activation of plasmacytoid dendritic cells is amplified in multiple sclerosis

HIGHLIGHTS

• who: Marta Corsetti and colleagues from the Department of Neuroscience "Lancisi", San Camillo Hospital, Rome, Italy have published the article: Resiquimod-Mediated Activation of Plasmacytoid Dendritic Cells Is Amplified in Multiple Sclerosis, in the Journal: (JOURNAL)
• what: The authors mimic viral infection using synthetic single-strand RNA Resiquimod and the authors compared the response of both DC subsets derived from healthy donors and MS patients by characterizing the expression of costimulatory molecules on the DC surface. The authors focused the attention on three major costimulatory molecules expressed on the DC surface known to activate T_cells . . .
  

   

  

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