Resistance mechanisms of the metastatic tumor microenvironment to anti-angiogenic therapy

HIGHLIGHTS

  • who: Lars M. Schiffmann from the Department of General, Visceral, Cancer and Transplantation Surgery, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany have published the Article: Resistance Mechanisms of the Metastatic Tumor Microenvironment to Anti-Angiogenic Therapy, in the Journal: (JOURNAL)
  • future: The exact mechanisms how circulating and metastasis infiltrating neutrophils/macrophages promote cancer progression remain to be elucidated but certainly more studies that discriminate between primary tumor and metastatic site are urgently needed. Future studies should engage models that involve metastasis and test their hypothesis in_(ideally) large human cohorts . . .

     

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