HIGHLIGHTS
- who: M van Dijk from the School National University have published the Article: Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways, in the Journal: (JOURNAL)
- what: The authors carried out a systematic analysis of the mechanisms that regulate TRAIL resistance in nontransformed cells. The authors show that non-transformed cells are protected from TRAIL-induced apoptosis by multiple, redundant pathways. The authors show that resistant tumour cells on the contrary tend to rely on the expression of only one of these anti-apoptotic proteins to maintain TRAIL resistance, which may . . .
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