Resistance to tyrosine kinase inhibitors promotes renal cancer progression through mcpip1 tumor-suppressor downregulation and c-met activation

HIGHLIGHTS

  • who: Paulina Marona from the (UNIVERSITY) have published the Article: Resistance to tyrosine kinase inhibitors promotes renal cancer progression through MCPIP1 tumor-suppressor downregulation and c-Met activation, in the Journal: (JOURNAL) of 20/05/2022
  • what: In the present report, the authors show that although sunitinib and sorafenib have overlapping target specificities, the mechanisms of resistance are distinct. The study was approved by the Hospital Institutional Review Board, and informed consent was obtained from each patient. In the present report, the authors show that along with the reduction in MCPIP1, the protein levels of . . .

     

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