HIGHLIGHTS
- who: Top from the Division of Cancer and Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, XN, UK have published the paper: resistant ovarian cancer cells to oncolytic adenovirus, in the Journal: (JOURNAL)
- what: The authors evaluate chromatin (histone) modification in chemoresistant cells and its relationship to Ad efficacy (wild-type or oncolytic Ad). To characterise the efficacy of the panel of Ads for this study, the authors sought to first determine the expression levels of CAR on primary epithelial ovarian cancer (EOC) cells cultured from clinical ascites (data not shown). The authors show . . .
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