Resolvin d1 inhibits the proliferation of osteoarthritis fibroblast-like synoviocytes through the hippo-yap signaling pathway

HIGHLIGHTS

• who: Siwei Su from the Human synovium was obtained from OA patients (n=4) who underwent artificial total knee arthroplasty at the Second Affiliated Hospital of Shandong First Medical UniversityPatients had advanced disease and were diagnosed with primary OA, excluding trauma and other structural causes of secondary OA. Control samples from healthy individuals (n=3) were obtained from patients at the time of knee arthroscopic evaluation. These patients were diagnosed as a result of knee injury caused by trauma to the knee or sport injury, excluding rheumatic diseases and inflammation. This study was approved by the Clinical . . .
  

   

  

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