Restoration of bdnf, darpp32, and d2r expression following intravenous infusion of human immature dental pulp stem cells in huntington’s disease 3-np rat model

HIGHLIGHTS

  • who: Cristiane Valverde Wenceslau and collaborators from the Universidade Federal Su00e3o Paulo (UNIFESP), Su00e3o Paulo, SP, Brazil have published the article: Restoration of BDNF, DARPP32, and D2R Expression Following Intravenous Infusion of Human Immature Dental Pulp Stem Cells in Huntingtonu2019s Disease 3-NP Rat Model, in the Journal: Cells 2022, 1664 of 28/04/2022
  • what: The study shows that intravenous transplantation of BDNF-secreting hIDPSC helps restore the endogenous BDNF expression and the expression of MSN markers (DARPP32 and D2R) in the striatum and cortex of the HD rat model.
  • how: To . . .

     

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