Restores the sensitivity of triple negative breast cancer cells to aminolevulinic acid-mediated photodynamic therapy

HIGHLIGHTS

  • who: ABCG and collaborators from the DepartmentUniversity of have published the paper: restores the sensitivity of triple negative breast cancer cells to aminolevulinic acid-mediated photodynamic therapy, in the Journal: Scientific Reports Scientific Reports
  • what: From this study have important implications for using ALA-based modalities for imaging and treating breast cancers.
  • how: To determine whether TNBC cells possess enhanced ABCG2 transporter activity the authors examined ABCG2 transporter activity in ALA-PDT-resistant TNBC cells and PDT-sensitive cells (T47D SkBr3) using a specific ABCG2 transporter probe pheophorbide a (Pha) together with a . . .

     

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