Results: five items were found to have an item content validity index (i-cvi) of 0.6, 2 of 0.5, and 2 of 0.2. the scale contentvalidity index (s-cvi) was found to be 0.80. regarding parental knowledge, the results show that almost all parents are able to correctly state the name of the diagnosis and the description and location of the heart defect. however, parental knowledge has important gaps; in particular, parents are less informed about the most characteristic sign of endocarditis, the possibility of contracting endocarditis more than once in a lifetime, and risk factors. parental knowledge also seems to be lacking regarding symptoms suggesting worsening health status in their children. conclusions: the italian version of the lkqchd has proved to be a valid tool to measure the level of knowledge of parents of children with chd, allowing to identify in which areas it is necessary to improve the education addressed to parents. key messages: assessing the knowledge of parents of children with chd allows to improve their education. the italian version of the lkqchd is a valid tool to measure the level of knowledge of parents of children with chd