Resveratrol reverses the warburg effect by targeting the pyruvate dehydrogenase complex in colon cancer cells

HIGHLIGHTS

  • who: Elise Saunier from the (UNIVERSITY) have published the research work: Resveratrol reverses the Warburg effect by targeting the pyruvate dehydrogenase complex in colon cancer cells, in the Journal: (JOURNAL) of 15/03/2017
  • what: The authors show that resveratrol (10 µM, 48 hr) induces both a cell growth arrest and a metabolic reprogramming in colon cancer cells. The authors show that resveratrol, at a concentration as low as 10 µM, reduces colon cancer cell proliferation and induces a metabolic reprograming leading to an increase of glucose oxidation, a decrease of lactate production, a decrease . . .

     

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