Retinal organoids from an aipl1 crispr/cas9 knockout cell line successfully recapitulate the molecular features of lca4 disease

HIGHLIGHTS

• who: Pedro R. L. Perdigu00e3o et al. from the Institute of Ophthalmology, University College London, London EC V EL, UK have published the paper: Retinal Organoids from an AIPL1 CRISPR/Cas9 Knockout Cell Line Successfully Recapitulate the Molecular Features of LCA4 Disease, in the Journal: (JOURNAL) of 21/03/2023
• what: The model recapitulates the molecular features of the LCA4 phenotype seen in other model types and therefore provides an alternative, complementary, model system to further interrogate the early molecular pathways involved in disease pathogenesis. The authors anticipate that the model described here will be . . .
  

   

  

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