Retinal photoreceptor protection in an amd-related mouse model by selective sigma-1 or sigma-2 receptor modulation

HIGHLIGHTS

  • who: Timur A. Mavlyutov et al. from the Department of Surgery, University of Wisconsin, Madison, WI, USA have published the research work: Retinal Photoreceptor Protection in an AMD-Related Mouse Model by Selective Sigma-1 or Sigma-2 Receptor Modulation, in the Journal: Genes 2022, 2386 of 14/Dec/2022
  • what: Since this model has shown promise in recapitulating salient characteristics of dry AMD , the authors used the same model in the current study.
  • how: The authors evaluated S1R- modulation in an model of Abca4-/-Rdh8-/- mice with disrupted visual cycle that predisposes . . .

     

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