Retinoic acid and rarγ maintain satellite cell quiescence through regulation of translation initiation

HIGHLIGHTS

• who: Wenzhe Luo from the EXPERIMENTAL PROCEDURES Animals Rosa26tdTomato/tdTomato mice were crossed with Pax7creER/creER mice to obtain the Pax7creER/+ have published the research work: Retinoic acid and RARu03b3 maintain satellite cell quiescence through regulation of translation initiation, in the Journal: (JOURNAL) of 18/09/2022
• how: These results showed that MyoD mature mRNA translation but not MyoD transcription or intron splicing was targeted by RA signaling in MuSCs. The authors identified a total of 36435 conservative RARu03b3 binding_sites across the genome and further integrated analysis revealed 1064 genes whose TSS region was bound . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.