HIGHLIGHTS
- who: Stuart Webb from the (UNIVERSITY) have published the research work: Retinoic acid receptor signaling preserves tendon stem cell characteristics and prevents spontaneous differentiation in vitro, in the Journal: (JOURNAL)
- what: The authors demonstrate that the effect of RAR compounds on TSCs is reversible by revealing their multi-lineage differentiation ability upon withdrawal of the compound. The authors have shown that maintaining Scx localization in the nucleus using a RAR agonist does not necessarily induce tenogenic differentiation but is rather associated with the maintenance of the TSC phenotype, consistent with the inhibition of differentiation towards . . .
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