Retrogene duplication and expression patterns shaped by the evolution of sex chromosomes in malaria mosquitoes

HIGHLIGHTS

SUMMARY

    The second trend is that autosomal retrogenes formed from parental genes on the X chromosome often exhibit male-biased expression. The study also found that 3 of 19 testis-biased expression is greater for retrogenes in the X-to-autosome duplication category compared to retrogenes originating from autosome-to-autosome duplication events. A genomic comparison between D. melanogaster, Ae. aegypti and Culex quinquefasciatus found a relative paucity of genes with male-biased expression on the Anopheles X chromosome, and it has been argued that the X-to-autosome retroposition of genes that evolve malebiased . . .

     

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