Revertant mosaicism in genodermatoses: natural gene therapy right before your eyes

HIGHLIGHTS

  • who: Peter C. van den Akker and collaborators from the Groningen Center for Blistering Diseases, Department of Genetics, University of Groningen, University Medical Center Groningen, RB Groningen, The Netherlands have published the article: Revertant Mosaicism in Genodermatoses: Natural Gene Therapy Right before Your Eyes, in the Journal: Biomedicines 2022, x of /2022/

SUMMARY

    For instance, while biallelic null-variants in ABCA12 cause the very severe harlequin type of ARCI, ‘milder' variants, usually missense or splice-site variants, cause a type of ARCI with or without a collodion membrane and erythroderma that is very . . .

     

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