HIGHLIGHTS
- who: Adi de la Zerda et al. from the DepartmentStanford University California, USA have published the research work: Review: Bioengineering strategies to probe T cell mechanobiology, in the Journal: (JOURNAL) of 29/03/2018
- what: This study shows that controlled AFM-delivered forces can transform an incapacitated T_cell to be operable by replacing the role of the actin cytoskeleton in forceactuation. This study showed that T_cells leverage mechanical forces to aid in cytotoxic activity against target cells. To summarize, regardless of the substrate chemistry, the stimulator identity, matrix coating method (chemical coupling or physical adsorption . . .
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