HIGHLIGHTS
- who: Chadwin Hanna Jr from the (UNIVERSITY) have published the research work: Review of meningioma diagnosis and management, in the Journal: (JOURNAL)
SUMMARY
Telomerase reverse_transcriptase (TERT) promoter gene alterations, which increase TERT expression and telomere length, conferring cell immortality, are linked to high-grade meningiomas with elevated rates of recurrence and poor clinical outcomes. Similarly, homologous deletion of the CDKN2A/B tumor suppressor genes has been identified as a marker of aggressive meningioma clinical course. While uncommon ( and amp;lt; 5%), loss of trimethylation expression of lysine 27 of histone H3 (H3K27me3) is . . .
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