Review of the use of animal models of human polycystic kidney disease for the evaluation of experimental therapeutic modalities

HIGHLIGHTS

• who: Shizuko Nagao and Tamio Yamaguchi from the Advanced Research Center for Animal Models of Human Diseases, Fujita Health University, Toyoake, Japan have published the research work: Review of the Use of Animal Models of Human Polycystic Kidney Disease for the Evaluation of Experimental Therapeutic Modalities, in the Journal: (JOURNAL)
• what: For a long time spontaneous animal models have been used as the primary focus for human diseases; however after the identification of the nucleotide sequence of the responsible genes PKD1 PKD2 PKHD1 and NPHPs various types of genetically modified models were developed by genetic . . .
  

   

  

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