Revisiting g3bp1 as a rasgap binding protein: sensitization of tumor cells to chemotherapy by the rasgap 317-326 sequence does not involve g3bp1

HIGHLIGHTS

  • who: RasGAP and colleagues from the Department of Physiology, University of Lausanne, Lausanne, Switzerland, Institut de Génétique Moleculaire de Montpellier UMR, IFR, Centre National de have published the research work: Revisiting G3BP1 as a RasGAP Binding Protein: Sensitization of Tumor Cells to Chemotherapy by the RasGAP 317-326 Sequence Does Not Involve G3BP1, in the Journal: (JOURNAL) of December/19,/2011
  • what: The evidence reported in this study shows that this hypothesis is incorrect.
  • how: Previous data indicated that G3BP1 binds to a discrete sequence of RasGAP within its SH3 domain . . .

     

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