Rewiring of glucose and lipid metabolism induced by g protein-coupled receptor 17 silencing enables the transition of oligodendrocyte progenitors to myelinating cells

HIGHLIGHTS

  • who: Davide Marangon and colleagues from the Department of Pharmaceutical Sciences, Università degli Studi di Milano, Milan, Italy have published the research work: Rewiring of Glucose and Lipid Metabolism Induced by G Protein-Coupled Receptor 17 Silencing Enables the Transition of Oligodendrocyte Progenitors to Myelinating Cells, in the Journal: Cells 2022, 11, x FOR PEER REVIEW of /2022/
  • what: The authors aim at elucidating the role of physiological GPR17 downregulation in OL metabolism by applying transcriptomics metabolomics and lipidomics on differentiating OLs.
  • how: The results showed that the number of GPR17-expressing cells . . .

     

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