Rho family gtpases and rho gefs in glucose homeostasis

HIGHLIGHTS

• who: Polly A. Machin and colleagues from the (UNIVERSITY) have published the paper: Rho Family GTPases and Rho GEFs in Glucose Homeostasis, in the Journal: Cells 2021, 915 of 13/04/2021
• what: Mouse models have been more widely used to study the roles of Rho GEFs than Rho GTPases, and this approach has shown that Rho GEFs are important regulators of glucose homeostasis in_vivo, with deficiencies or deregulated expression commonly resulting in impaired insulin signaling, insulin resistance, glucose intolerance, and the development of metabolic syndrome and type 2 diabetes.
• how: It should . . .
  

   

  

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