Rhob affects colitis through modulating cell signaling and intestinal microbiome

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  • who: Jianming Yang from the All mice were generated on the C BL/ J backgroundRhoB heterozygous (RhoB+/-) and homozygous knockout (RhoB-/-) mice were generated at the Shanghai Biomodel Organisms Center (Shanghai, China) and were confirmed by PCR genotype analysis [19]. Wild type male C BL/ J mice were purchased from Academy of Military Medical Science (Bejing, China). All mice were maintained in a specific pathogen free condition in the Department of Laboratory Animal Science and Technology of Tianjin Medical University. Unless otherwise stated, all mice were used for experiments at, weeks of age. All mice experiments were . . .

     

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