Rhogdi sumoylation at lys-138 increases its binding activity to rho gtpase and its inhibiting cancer cell motility*

HIGHLIGHTS

  • who: Jianxiu Yu from the (UNIVERSITY) have published the Article: RhoGDI SUMOylation at Lys-138 Increases Its Binding Activity to Rho GTPase and Its Inhibiting Cancer Cell Motility*, in the Journal: (JOURNAL) of April/20,/2012
  • what: Although the studies reported here provided clear evidence for the XIAP negative regulation of SUMO-RhoGDI, the authors had no direct evidence showing whether the XIAP-RhoGDI interaction results in an increase of the de-SUMOylation process or a decrease of SUMOylation conjugation of RhoGDI.
  • how: The results showed that during the first 2 days when . . .

     

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