Ribosome-binding domain of eukaryotic initiation factor-2 kinase gcn2 facilitates translation control*

HIGHLIGHTS

  • who: Shuhao Zhu from the (UNIVERSITY) have published the Article: Ribosome-binding Domain of Eukaryotic Initiation Factor-2 Kinase GCN2 Facilitates Translation Control*, in the Journal: (JOURNAL) of September/24,/1997
  • how: To further characterize the interaction of the carboxyl-terminal portion of GCN2 with ribosomes the authors carried out sedimentation analysis in the absence of Mg21 leading to the dissociation of ribosomes into free 40 S and 60 S particles. This model implies that the uncharged tRNA levels in the cell can be more efficiently monitored by GCN2 when the kinase is associated with . . .

     

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