Ripk3 promoter hypermethylation in hepatocytes protects from bile acid-induced inflammation and necroptosis

HIGHLIGHTS

• who: Jessica Hoff from the Mice Male and female FVB/N(Rj) mice at, weeks of age were used for all experimentsFVB/N(Rj) mice were partially bred within the Jena University Hospital animal facility under specific pathogen-free conditions and purchased from Janvier Labs. The animals had access to conventional rodent chow and water ad libitum. They were maintained under a constant humidity (50-60%), a, h light/dark cycle (incl. , min dim phases), and a constant temperature (, u00b0C). All experimental protocols were approved by the ethics committee and local government authorities in Thuringia, Germany (UKJ . . .
  

   

  

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