Risk and benefit for umbrella trials in oncology: a systematic review and meta-analysis

HIGHLIGHTS

  • who: Karolina Strzebonska from the Jagiellonian University Medical College, Kraków, Poland have published the research: Risk and benefit for umbrella trials in oncology: a systematic review and meta-analysis, in the Journal: (JOURNAL)
  • what: The aim of the systematic review with meta-analysis was to evaluate the efficacy and safety profiles in cancer umbrella trials testing targeted drugs or a combination of targeted therapy with chemotherapy.
  • how: For PFS and OS analyses the authors used medians provided by the study authors. The authors analyzed 9 drug-related grade 5 AEs among 999 . . .

     

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