HIGHLIGHTS
SUMMARY
Of biological monitoring of the unfractionated heparin effect have contributed to a pragmatic stance concerning dose adjustments. This study was conducted to assess the variability in UFH dosing and its clinical and biological anticoagulatory effects during hemodialysis in a prevalent cohort, and to identify explanatory factors of heparin dosing. Upon the start of chronic hemodialysis, UFH is administered according to a standing order using a loading dose of 2,500 IU UFH and a maintenance dose of 1,400 IU UFH/hour until completion of the hemodialysis session in case of catheter use and . . .
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