Risk of early neurodevelopmental disorders associated with in utero exposure to valproate and other antiepileptic drugs: a nationwide cohort study in france

HIGHLIGHTS

  • who: Joël Coste from the cohort study in FrancePSL University have published the research work: Risk of early neurodevelopmental disorders associated with in utero exposure to valproate and other antiepileptic drugs: a nationwide cohort study in France, in the Journal: Scientific Reports Scientific Reports
  • what: This study confirms a four to fivefold increased risk of early NDs (before the age of 6 years), especially pervasive developmental disorders and mental retardation, associated with exposure to VPA indicated in epilepsy during pregnancy, with a marked dose effect.
  • future: The limited follow-up in the . . .

     

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