Rk-33, a small molecule inhibitor of host rna helicase ddx3, suppresses multiple variants of sars-cov-2

HIGHLIGHTS

  • who: Kylene Kehn-Hall and Venu Raman from the Harbin Institute of Technology, Shenzhen, China Peking University, China have published the Article: RK-33, a small molecule inhibitor of host RNA helicase DDX3, suppresses multiple variants of SARS-CoV-2, in the Journal: (JOURNAL)
  • what: The authors report on the importance of DDX3 and its targeting by the small_molecule inhibitor RK-33 which was developed earlier by rational drug design that resulted in a unique structural scaffold with little or no toxicity in animals (Kondaskar et_al, 2010; Bol et_al, 2015; Xie et_al, 2016; Heerma van . . .

     

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