Rn7sk small nuclear rna controls bidirectional transcription of highly expressed gene pairs in skin

HIGHLIGHTS

  • who: Roberto Bandiera from the University of Krebsforschungszentrum (DKFZ), Im Neuenheimer Feld, Heidelberg, Germany have published the paper: RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors show that human RN7SK sustained Pol II activity at highly expressed 8 bidirectionally transcribed gene pairs. The authors propose that the 7SK ribonuclear complex tethers P-TEFb and other transcriptional regulators to highly transcribed bidirectional promoters to regulate Pol II activity. The work demonstrates that the precise coordination of highly expressed bidirectional gene . . .

     

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