Rna is a critical element for the sizing and the composition of phase-separated rna⠍protein condensates

HIGHLIGHTS

  • who: Marina Garcia-Jove Navarro from the École PSL University have published the article: RNA is a critical element for the sizing and the composition of phase-separated RNA⠍protein condensates, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors focused on NORAD, a highly conserved and abundant long noncoding RNA (lncRNA), which has been described as a multivalent binding-platform of PUM proteins and, by there, a key regulator of their activity34.
  • how: Similar results were obtained with two other Pumilio 1 targets PUM2 and Rad21 mRNAs which were also recruited . . .

     

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