Rna polymerase iii transcription and cancer: a tale of two rpc7 subunits

HIGHLIGHTS

  • who: Pol III and colleagues from the Lehigh University, United States have published the research: RNA polymerase III transcription and cancer: A tale of two RPC7 subunits, in the Journal: (JOURNAL)
  • what: By examining the reported similarities and differences in RPC7 subunit sequence and activities during development and disease, the authors seek to re-visit the question: are RPC7u03b1 and RPC7u03b2 subunits functionally redundant? Instead, differences in Pol III identity, determined by the presence of RPC7u03b1 or RPC7u03b2, are likely to influence Pol III transcription and cell transformation through alternate mechanisms that the authors explore . . .

     

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