Rna sensor mda5 suppresses line-1 retrotransposition by regulating the promoter activity of line-1 5′-utr

HIGHLIGHTS

• who: Jiaxiu Yan from the Department of Clinical Laboratory, First Hospital of Jilin University, Changchun, Jilin, China have published the Article: RNA sensor MDA5 suppresses LINE-1 retrotransposition by regulating the promoter activity of LINE-1 5u2032-UTR, in the Journal: (JOURNAL)
• what: The authors focused on the LINE-1 5u2032-UTR, and tested whether MDA5-myc could affect the promoter activity of LINE-1 5u2032-UTR in a firefly luciferase reporter assay (Fig 5H). Intriguingly, although the authors focused on MDA5u2032-mediated suppression of LINE-1 5u2032-UTR, it appeared that MDA5 can suppress . . .
  

   

  

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