Rnase p ribozyme effectively inhibits human cc-chemokine receptor 5 expression and human immunodeficiency virus 1 infection

HIGHLIGHTS

• who: Bin Yan and collaborators from the School of Public Health, University of California, Berkeley, CA, USA have published the Article: RNase P Ribozyme Effectively Inhibits Human CC-Chemokine Receptor 5 Expression and Human Immunodeficiency Virus 1 Infection, in the Journal: (JOURNAL)
• what: The authors showed that a ribozyme variant with two novel point mutations exhibited about 30-fold higher cleavage activity than that of the wildtype M1RNA sequence. The anti-CCR5 RNase P ribozyme-based approach focuses on a cellular gene, targeting the entry step of HIV , and therefore should minimize the generation of . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.