HIGHLIGHTS
- who: RNF and colleagues from the State Key Laboratory of Virology, Medical Research Institute, College of Life Sciences, Wuhan University, Wuhan, China have published the article: RNF26 Temporally Regulates Virus-Triggered Type I Interferon Induction by Two Distinct Mechanisms, in the Journal: (JOURNAL) of September/25,/2014
- what: The authors identified an E3 ubiquitin ligase RING finger protein 26 (RNF26) that targeted MITA for K11-linked polyubiquitination upon viral infection. The authors demonstrated that RNF26 but not the enzymatic inactive mutants induced polyubiquitination of MITA.
- how: Similar results were obtained with various RNA . . .
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