Robokod: microbial strain design for (over)production of target compounds

HIGHLIGHTS

  • who: Natalie J. Stanford from the Institute of Biotechnology, University of, UK, School of Computer Science, University have published the research: RobOKoD: microbial strain design for (over)production of target compounds, in the Journal: (JOURNAL)
  • what: Once the first knockout is predicted, the model is modified to block this reaction, and the same selection process is used to select the second reaction to delete.
  • how: This approach is not optimal as it limits the amount of network information that can be used discounts metabolic complexity and therefore prevents predictions of less intuitive metabolic . . .

     

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