Rock inhibition with y-27632 reduces joint inflammation and damage in serum-induced arthritis model and decreases in vitro osteoclastogenesis in patients with early arthritis

HIGHLIGHTS

  • who: Angela Rodrí from the University of Gothenburg, Sweden United States have published the Article: ROCK inhibition with Y-27632 reduces joint inflammation and damage in serum-induced arthritis model and decreases in vitro osteoclastogenesis in patients with early arthritis, in the Journal: (JOURNAL)
  • what: The in_vitro assays performed in this work have other remarkable aspects. The work has confirmed the attenuation of experimental arthritis by Y-27632 treatment, including the new aspect of a specific decrease of osteoclastogenesis without a negative impact on osteogenesis.
  • how: There are several pieces of evidence . . .

     

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