Role for formin-like 1-dependent acto-myosin assembly in lipid droplet dynamics and lipid storage

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  • who: Simon G. Pfisterer from the Department of Anatomy and Research Programs Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finland, Minerva Foundation Institute for have published the research: Role for formin-like 1-dependent acto-myosin assembly in lipid droplet dynamics and lipid storage, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 31/03/2017
  • what: The authors propose a novel acto-myosin structure regulating lipid storage: FMNL1-dependent assembly of myosin II-functionalized actin filaments on LDs facilitates their dissociation thereby affecting LD surface-to-volume ratio and enzyme accessibility to TGs. The . . .

     

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