HIGHLIGHTS
- who: Satish Pasula et al. from the (UNIVERSITY) have published the research: Role of casein kinase 1 in the glucose sensor-mediated signaling pathway in yeast, in the Journal: (JOURNAL)
- what: The authors examined whether the glucose sensors directly couple with Yck1/2 to convert glucose binding into an intracellular signal that leads to the degradation of Mth1.
SUMMARY
Subsequent studies have shown that the plasma_membrane-tethered casein kinases Yck1/2 phosphorylate Mth1, triggering its ubiquitination and subsequent degradation. It has also been shown by yeast-two-hybrid assay that Mth1 . . .
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