Role of cockayne syndrome group b protein in replication stress: implications for cancer therapy

HIGHLIGHTS

  • who: John R. Walker and Xu-Dong Zhu from the Department of Biology, McMaster University, Hamilton, ON L S , Canada have published the research work: Role of Cockayne Syndrome Group B Protein in Replication Stress: Implications for Cancer Therapy, in the Journal: (JOURNAL)

SUMMARY

    Accurate replication of genomic DNA is essential to ensuring faithful transmission of genetic_information during cell division. DNA replication is initiated at multiple origins and up to thousands of replication forks are established at a given time in S phase. Timely coordination of these replication forks is critical to ensure . . .

     

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