HIGHLIGHTS
- who: Renju Pun from the La Trobe University, Australia have published the article: Role of Connexin 43 phosphorylation on Serine-368 by PKC in cardiac function and disease, in the Journal: (JOURNAL)
- future: Studies are required to assess the significance of this relationship in myocarditis and if the PKC/Cx43 pathway can serve as a novel therapeutic target to alleviate consequences associated with myocarditis. Mitochondrial hemichannel opening is reduced in cardiomyocytes isolated from mice harboring a knockin mutation for Cx43 S368A suggesting further that mitochondrial hemichannels are targeted by PKC in cardiac cells however more . . .
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