Role of extracellular matrix architecture and signaling in melanoma therapeutic resistance

HIGHLIGHTS

  • who: Ana Popovic from the University of Texas MD Anderson Cancer Center, United States have published the Article: Role of extracellular matrix architecture and signaling in melanoma therapeutic resistance, in the Journal: (JOURNAL)
  • what: It is important to note that the studies discussed in this section employed in_vitro (e_g, hydrogels or decellularized matrices) or animal models to investigate the role of ECM alignment and stiffness in melanoma progression, in particular during melanoma cell migration and invasion.
  • how: The data indicated that mutations in BRAF are prevalent in 50% of melanoma patient samples followed . . .

     

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