Role of h4k16 acetylation in 53bp1 recruitment to double-strand break sites in in vitro aged cells

HIGHLIGHTS

  • who: Lourdes González-Bermúdez from the IDIBELL, Hospitalet de Llobregat, Spain have published the paper: Role of H4K16 acetylation in 53BP1 recruitment to double-strand break sites in in vitro aged cells, in the Journal: (JOURNAL)
  • what: In the work , H4K16Ac levels were assessed by immunofluorescence over different culture passages 1 h after Bleocin treatment (Fig 2C and D). The authors show that, as HDFs age, their H4K16Ac levels are lower with every passage when compared to younger cells. The data presented in this study show that MOF and H4K16Ac levels are reduced . . .

     

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