Role of matrix metalloprotease-2 and mmp-9 in experimental lung fibrosis in mice

HIGHLIGHTS

  • who: Tina Bormann from the (UNIVERSITY) have published the research work: Role of matrix metalloprotease-2 and MMP-9 in experimental lung fibrosis in mice, in the Journal: (JOURNAL)
  • what: The authors have examined the role of single MMP-2 or MMP-9 deletion and of combined MMP-2/-9 double deletion in a well-defined murine model of lung fibrosis induced by adenoviral exposure to biologically active TGF-u03b21. Since many of the MMPs, including MMP-2 and MMP9, are able to activate latent TGF-u03b2 in_vitro the authors examine TGF-u03b21 levels in . . .

     

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