HIGHLIGHTS
- who: NICOLE M. KANE et al. from the University of Glasgow, Glasgow, United Kingdom have published the research work: Role of MicroRNAs 99b, 181a, and 181b in the Differentiation of Human Embryonic Stem Cells to Vascular Endothelial Cells, in the Journal: (JOURNAL)
- what: The authors show that the reduction of miRNA maturation induced by Dicer knockdown suppressed hES-EC differentiation. The authors report that augmentation of miRNAs by gene transfer can potentiate the endothelial differentiation capacity in a hESC line that evokes relatively poor differentiation to ECs. The authors demonstrate that the transplantation of hESC . . .
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